Uniprot ID: | P09382 |
Secondary ID: | B2R5E8, Q9UDK5 |
Symbol: | LGALS1 |
Other Name: | Gal-1,14 kDa laminin-binding protein,HLBP14,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,S-Lac lectin 1 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Apoptosis |
Category I | Category II | Category III |
---|---|---|
Extracellular | Secreted protein |
Reference Record 1
PubMed ID | 28887481 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,HSCs migration | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β and PDGF-like signals |
Reference Record 2
PubMed ID | 24928277 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | fibroblasts activation,fibroblasts differentiation | ||
Process III | |||
Mechanism | Targeting TGF-β1 |