Ephrin-B2

Basic Information


Uniprot ID: P52799
Secondary ID: Q5JV56
Symbol: EFNB2
Other Name: EPLG5,EPH-related receptor tyrosine kinase ligand 5,LERK-5,HTK ligand,HTK-L
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Developmental protein,Host cell receptor for virus entry,Receptor


Target Classification


Category I Category II Category III
Extracellular Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28743805 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II myofibroblasts activation
Process III prevenet collagen deposition
Mechanism Targeting Stat3 and TGF-β/Smad3 signaling