Tripartite motif-containing protein 72

Basic Information


Uniprot ID: Q6ZMU5
Secondary ID: Q8N4X6, Q8NBD9
Symbol: TRIM72
Other Name: MG53,Mitsugumin-53,Mg53
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Exocytosis,Transport


Target Classification


Category I Category II Category III
Extracellular Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26985866 Compound ID
CAS Name
Model vitro Fibrosis Disease Cardiac fibrosis
Process I
Process II fibroblasts proliferation,fibroblast migration
Process III
Mechanism Targeting TGF-β signaling pathway

Reference Record 2

PubMed ID 25637627 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism