Rap guanine nucleotide exchange factor 3

Basic Information


Uniprot ID: O95398
Secondary ID: A8K2G5
Symbol: RAPGEF3
Other Name: CGEF1,Exchange factor directly activated by cAMP 1,Exchange protein directly activated by cAMP 1,EPAC 1,Rap1 guanine-nucleotide-exchange factor directly activated by cAMP,cAMP-regulated guanine nucleotide exchange factor I,cAMP-GEFI
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Guanine-nucleotide releasing factor


Target Classification


Category I Category II Category III
Extracellular Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27206858 Compound ID
CAS Name
Model vitro Fibrosis Disease Cystic fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 26854595 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation,HSCs activation
Process III prevenet collagen deposition
Mechanism Targeting Rap1