Mitogen-activated protein kinase kinase kinase 19

Basic Information

Uniprot ID:	Q56UN5
Secondary ID:	B2RP57
Symbol:	MAP3K19
Other Name:	RCK,Regulated in COPD, protein kinase,SPS1STE20-related protein kinase YSK4
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I	Category II	Category III
Intracellular	Enzyme	Kinase

Related Compound

Target ID	Name	Interaction
D0599	Compound A	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	27144281	Compound ID	D0599
CAS		Name	Compound A
Model	vitro,human	Fibrosis Disease	Idiopathic pulmonary fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting TGF-β signaling