Uniprot ID: | O43353 |
Secondary ID: | B7Z748, Q6UWF0 |
Symbol: | RIPK2 |
Other Name: | CARDIAK,CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Kinase,Serine/threonine-protein kinase,Transferase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Kinase |
Reference Record 1
PubMed ID | 26463597 | Compound ID | |
CAS | Name | ||
Model | human,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting NF-κB and p38 signalling |