MAP kinase-activated protein kinase 2

Basic Information

Uniprot ID: P49137
Secondary ID: Q5SY30, Q5SY41, Q8IYD6
Symbol: MAPKAPK2
Other Name:
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I Category II Category III
Intracellular Enzyme Kinase

Related Compound

Target ID Name Interaction
D0984 MMI-0100 inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 23470623 Compound ID D0984
CAS 1039342-24-9 Name MMI-0100
Model human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I attenue inflammation
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 17600313 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II fibroblasts proliferation,myofibroblasts differentiation,fibroblasts migration
Process III prevenet collagen deposition
Mechanism