Receptor tyrosine-protein kinase erbB-2

Basic Information


Uniprot ID: P04626
Secondary ID: B2RZG3
Symbol: ERBB2
Other Name: HER2,Metastatic lymph node gene 19 protein,MLN 19,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface receptor HER2,p185erbB2,
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,Kinase,Receptor,Transferase,Tyrosine-protein kinase


Target Classification


Category I Category II Category III
Intracellular Enzyme Kinase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27882385 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Keloid
Process I
Process II fibroblasts migration
Process III prevenet collagen deposition
Mechanism Targeting ErbB2-mediated signaling