Tyrosine-protein phosphatase non-receptor type 11

Basic Information


Uniprot ID: Q06124
Secondary ID: A8K1D9, Q96HD7
Symbol: PTPN11
Other Name: PTP2C,Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Hydrolase,Protein phosphatase


Target Classification


Category I Category II Category III
Intracellular Enzyme Phosphatase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27736153 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts-to-myofibroblasts,fibroblasts proliferation,fibroblasts apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 22362894 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism