Uniprot ID: | Q06124 |
Secondary ID: | A8K1D9, Q96HD7 |
Symbol: | PTPN11 |
Other Name: | PTP2C,Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3 |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Hydrolase,Protein phosphatase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Phosphatase |
Reference Record 1
PubMed ID | 27736153 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | fibroblasts-to-myofibroblasts,fibroblasts proliferation,fibroblasts apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 2
PubMed ID | 22362894 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | cells apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism |