| Uniprot ID: | P18031 |
| Secondary ID: | Q5TGD8, Q9BQV9, Q9NQQ4 |
| Symbol: | PTPN1 |
| Other Name: | PTP1B,Protein-tyrosine phosphatase 1B,PTP-1B |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Hydrolase,Protein phosphatase |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Enzyme | Phosphatase |
Reference Record 1
| PubMed ID | 27207947 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 26739621 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs proliferation | ||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 22446161 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 4
| PubMed ID | 28987240 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||