Uniprot ID: | Q9P212 |
Secondary ID: | A6NGW0 |
Symbol: | PLCE1 |
Other Name: | KIAA1516,Pancreas-enriched phospholipase C,Phosphoinositide phospholipase C-epsilon-1,Phospholipase C-epsilon-1,PLC-epsilon-1 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Guanine-nucleotide releasing factor,Hydrolase,Transducer |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Phosphodiesterase |
Reference Record 1
PubMed ID | 28093232 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Scar |
Process I | regulate cytokines and growth factors | ||
Process II | keratinocyte proliferation,keratinocyte migration | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting Col6a1, Col17a1 and Ccl20 |