E3 ubiquitin-protein ligase NEDD4-like

Basic Information


Uniprot ID: Q96PU5
Secondary ID: O43165
Symbol: NEDD4L
Other Name: KIAA0439,HECT-type E3 ubiquitin transferase NED4L,NEDD4.2,Nedd4-2
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Transferase


Target Classification


Category I Category II Category III
Intracellular Enzyme Ligase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28862701 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism