Uniprot ID: | P78317 |
Secondary ID: | B2R6D6, D6RF58, Q49AR8 |
Symbol: | RNF4 |
Other Name: | SNURF,RING finger protein 4,RING-type E3 ubiquitin transferase RNF4,Small nuclear ring finger protein,Protein SNURF |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Activator,DNA-binding,Transferase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Ligase |
Reference Record 1
PubMed ID | 28143738 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation,regulate cytokines and growth factors | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β signaling |