Uniprot ID: | Q00987 |
Secondary ID: | A6NL51 |
Symbol: | MDM2 |
Other Name: | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Transferase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Ligase |
Reference Record 1
PubMed ID | 21747166 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,cells apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting p53/CTGF |