E3 ubiquitin-protein ligase pellino homolog 1

Basic Information


Uniprot ID: Q96FA3
Secondary ID: Q96SM0, Q9GZY5, Q9HCX0
Symbol: PELI1
Other Name: PRISM,Pellino-1,Pellino-related intracellular-signaling molecule,RING-type E3 ubiquitin transferase pellino homolog 1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Transferase


Target Classification


Category I Category II Category III
Intracellular Enzyme Ligase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 25446187 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I
Process II fibroblasts activation,fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting NF-κB and AP-1