Uniprot ID: | Q96FA3 |
Secondary ID: | Q96SM0, Q9GZY5, Q9HCX0 |
Symbol: | PELI1 |
Other Name: | PRISM,Pellino-1,Pellino-related intracellular-signaling molecule,RING-type E3 ubiquitin transferase pellino homolog 1 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Transferase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Ligase |
Reference Record 1
PubMed ID | 25446187 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts activation,fibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting NF-κB and AP-1 |