Arginase-1

Basic Information

Uniprot ID: P05089
Secondary ID: A6NEA0
Symbol: ARG1
Other Name: Liver-type arginase,Type I arginase
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Hydrolase

Target Classification

Category I Category II Category III
Intracellular Enzyme Hydrolase

Related Compound

Target ID Name Interaction
D0398 Nor-noha inhibitor
D0568 S-(2-Boronoethyl)-L-cysteine inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 25807386 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Arterial fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 21640975 Compound ID D0568
CAS 63107-40-4 Name S-(2-Boronoethyl)-L-cysteine
Model mice Fibrosis Disease Intestinal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 20219858 Compound ID D0398
CAS 189302-40-7 Name Nor-noha
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism