Uniprot ID: | Q9UMW8 |
Secondary ID: | Q53Y90, Q6IAD9, Q9NY71 |
Symbol: | USP18 |
Other Name: | ISG43,43 kDa ISG15-specific protease,hUBP43,ISG15-specific-processing protease,Ubl thioesterase 18 |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Hydrolase,Protease,Thiol protease |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Hydrolase |
Reference Record 1
PubMed ID | 27572150 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β-activated kinase 1-p38/c-Jun N-terminal kinase 1/2 signaling axis |