Proteasome subunit beta type-10

Basic Information


Uniprot ID: P40306
Secondary ID: B2R5J4, Q5U098
Symbol: PSMB10
Other Name: LMP10,Low molecular mass protein 10,Macropain subunit MECl-1,Multicatalytic endopeptidase complex subunit MECl-1,Proteasome MECl-1,Proteasome subunit beta-2i
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Hydrolase,Protease,Threonine protease


Target Classification


Category I Category II Category III
Intracellular Enzyme Hydrolase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28478040 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting IκBα/NF-κB and TGF-β1/Smad2/3 signaling