Uniprot ID: | P40306 |
Secondary ID: | B2R5J4, Q5U098 |
Symbol: | PSMB10 |
Other Name: | LMP10,Low molecular mass protein 10,Macropain subunit MECl-1,Multicatalytic endopeptidase complex subunit MECl-1,Proteasome MECl-1,Proteasome subunit beta-2i |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Hydrolase,Protease,Threonine protease |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Hydrolase |
Reference Record 1
PubMed ID | 28478040 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting IκBα/NF-κB and TGF-β1/Smad2/3 signaling |