Poly [ADP-ribose] polymerase 1

Basic Information


Uniprot ID: P09874
Secondary ID: B1ANJ4, Q8IUZ9
Symbol: PARP1
Other Name: ADPRT,PARP-1,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: DNA-binding,Glycosyltransferase,Transferase


Target Classification


Category I Category II Category III
Intracellular Enzyme Transferase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 22073128 Compound ID
CAS Name
Model vitro Fibrosis Disease Vascular fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 18287562 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 16632544 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism