Uniprot ID: | P63279 |
Secondary ID: | D3DU69 |
Symbol: | UBE2I |
Other Name: | UBC9,RING-type E3 SUMO transferase UBC9,SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Transferase |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Transferase |
Reference Record 1
PubMed ID | 28143738 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation,regulate cytokines and growth factors | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β signaling |