Carbonyl reductase [NADPH] 1

Basic Information


Uniprot ID: P16152
Secondary ID: B2RBZ7, B4DFK7, Q3LHW8
Symbol: CBR1
Other Name: CBR,15-hydroxyprostaglandin dehydrogenase [NADP(+)],NADPH-dependent carbonyl reductase 1,Prostaglandin 9-ketoreductase,Prostaglandin-E(2) 9-reductase,Short chain dehydrogenasereductase family 21C member 1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Oxidoreductase


Target Classification


Category I Category II Category III
Intracellular Enzyme Oxidoreductase

Related Compound


Target ID Name Interaction
D0005 Rutin inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 28826911 Compound ID D0005
CAS 153-18-4 Name Rutin
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Akt and MAPK pathways