Protein-lysine 6-oxidase

Basic Information

Uniprot ID: P28300
Secondary ID: B2R5Q3, Q5FWF0
Symbol: LOX
Other Name: Lysyl oxidase
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Oxidoreductase

Target Classification

Category I Category II Category III
Intracellular Enzyme Oxidoreductase

Related Compound

Target ID Name Interaction
D0168 Aminopropionitrile inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 26670953 Compound ID D0168
CAS 151-18-8 Name Aminopropionitrile
Model vitro,rat Fibrosis Disease Pulmonary fibrosis
Process I
Process II EMT
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 24574233 Compound ID
CAS Name
Model human Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 21665949 Compound ID D0168
CAS 151-18-8 Name Aminopropionitrile
Model vitro,mice Fibrosis Disease Bone marrow fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 21215756 Compound ID D0168
CAS 151-18-8 Name Aminopropionitrile
Model vitro,human,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 19546236 Compound ID D0168
CAS 151-18-8 Name Aminopropionitrile
Model vitro,mice Fibrosis Disease Tissue fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 29125826 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism