Phospholipid hydroperoxide glutathione peroxidase

Basic Information


Uniprot ID: P36969
Secondary ID: O43381, Q6PJ59, Q9UPK2
Symbol: GPX4
Other Name: PHGPx,Glutathione peroxidase 4,GPx-4,GSHPx-4
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Developmental protein,Oxidoreductase,Peroxidase


Target Classification


Category I Category II Category III
Intracellular Enzyme Oxidoreductase

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26042203 Compound ID
CAS Name
Model mice,human Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism