Caspase-2

Basic Information


Uniprot ID: P42575
Secondary ID: A8K5F9
Symbol: CASP2
Other Name: ICH1,CASP-2,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD-2,Protease ICH-1,Caspase-2 subunit p18,Caspase-2 subunit p13,Caspase-2 subunit p12
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Hydrolase,Protease,Thiol protease


Target Classification


Category I Category II Category III
Intracellular Enzyme Protease

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26890135 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 25053716 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II HSCs activation,cells apoptosis
Process III prevenet collagen deposition
Mechanism