Uniprot ID: | P42575 |
Secondary ID: | A8K5F9 |
Symbol: | CASP2 |
Other Name: | ICH1,CASP-2,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD-2,Protease ICH-1,Caspase-2 subunit p18,Caspase-2 subunit p13,Caspase-2 subunit p12 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Hydrolase,Protease,Thiol protease |
Category I | Category II | Category III |
---|---|---|
Intracellular | Enzyme | Protease |
Reference Record 1
PubMed ID | 26890135 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 2
PubMed ID | 25053716 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Liver fibrosis |
Process I | attenue inflammation | ||
Process II | HSCs activation,cells apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism |