Uniprot ID: | Q15466 |
Secondary ID: | F1D8P5, Q5QP36 |
Symbol: | NR0B2 |
Other Name: | SHP,Orphan nuclear receptor SHP,Small heterodimer partner |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Receptor,Repressor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Nuclear receptor | NR0 family |
Reference Record 1
PubMed ID | 25976932 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation | ||
Process III | |||
Mechanism | Targeting TGF-β |
Reference Record 2
PubMed ID | 19643931 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting PAI-1 |