Uniprot ID: | Q14994 |
Secondary ID: | E9PB75 |
Symbol: | NR1I3 |
Other Name: | CAR,Constitutive activator of retinoid response,Constitutive active response,Constitutive androstane receptor,CAR,Orphan nuclear receptor MB67 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Activator,DNA-binding,Receptor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Nuclear receptor | NR1 family |
Reference Record 1
PubMed ID | 25155144 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Dermal fibrosis |
Process I | |||
Process II | myofibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGFβ signaling |