Nuclear receptor subfamily 1 group I member 3

Basic Information


Uniprot ID: Q14994
Secondary ID: E9PB75
Symbol: NR1I3
Other Name: CAR,Constitutive activator of retinoid response,Constitutive active response,Constitutive androstane receptor,CAR,Orphan nuclear receptor MB67
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding,Receptor


Target Classification


Category I Category II Category III
Intracellular Nuclear receptor NR1 family

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 25155144 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Dermal fibrosis
Process I
Process II myofibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting TGFβ signaling