Nuclear receptor ROR-gamma

Basic Information


Uniprot ID: P51449
Secondary ID: Q5SZR9, Q8N5V7, Q8NCY8
Symbol: RORC
Other Name: NR1F3,Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Activator,Developmental protein,DNA-binding,Receptor


Target Classification


Category I Category II Category III
Intracellular Nuclear receptor NR1 family

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27791279 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II EMT
Process III prevenet collagen deposition
Mechanism Targeting Tgfbr1 and Smad2