Uniprot ID: | P10275 |
Secondary ID: | A0A0B4J1T2 |
Symbol: | AR |
Other Name: | DHTR,Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Activator,DNA-binding,Receptor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Nuclear receptor | NR3 family |
Reference Record 1
PubMed ID | 23150236 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Liver fibrosis |
Process I | attenue inflammation | ||
Process II | HSCs activation,HSCs proliferation,cells migration | ||
Process III | |||
Mechanism | Targeting IL1R/IL1Ra signaling |