Uniprot ID: | P43354 |
Secondary ID: | Q16311, Q53RZ2, Q6NXU0 |
Symbol: | NR4A2 |
Other Name: | NOT,Immediate-early response protein NOT,Orphan nuclear receptor NURR1,Transcriptionally-inducible nuclear receptor |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | DNA-binding,Receptor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Nuclear receptor | NR4 family |
Reference Record 1
PubMed ID | 27646469 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSC apoptosis,HSC migration | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting MAPK pathway |
Reference Record 2
PubMed ID | 26713258 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,HSCs proliferation | ||
Process III | |||
Mechanism | Targeting MAPK pathway |