Nuclear receptor subfamily 4 group A member 2

Basic Information


Uniprot ID: P43354
Secondary ID: Q16311, Q53RZ2, Q6NXU0
Symbol: NR4A2
Other Name: NOT,Immediate-early response protein NOT,Orphan nuclear receptor NURR1,Transcriptionally-inducible nuclear receptor
Class: Single Protein
Type: anti-fibrotic
Molecular Function: DNA-binding,Receptor


Target Classification


Category I Category II Category III
Intracellular Nuclear receptor NR4 family

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27646469 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSC apoptosis,HSC migration
Process III prevenet collagen deposition
Mechanism Targeting MAPK pathway

Reference Record 2

PubMed ID 26713258 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,HSCs proliferation
Process III
Mechanism Targeting MAPK pathway