| Uniprot ID: | P42224 |
| Secondary ID: | A8K989 |
| Symbol: | STAT1 |
| Other Name: | Transcription factor ISGF-3 components p91p84 |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Activator,DNA-binding |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other transcription factor | Transcription activator |
Reference Record 1
| PubMed ID | 17133483 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs proliferation,cells apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β signaling | ||
Reference Record 2
| PubMed ID | 16212889 | Compound ID | |
| CAS | Name | ||
| Model | rat | Fibrosis Disease | Idiopathic pulmonary fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||