| Uniprot ID: | O15105 |
| Secondary ID: | B7Z773 |
| Symbol: | SMAD7 |
| Other Name: | MADH7,MAD homolog 7,Mothers against DPP homolog 7,Mothers against decapentaplegic homolog 8,MAD homolog 8,Mothers against DPP homolog 8,SMAD family member 7,SMAD 7,Smad7,hSMAD7 |
| Class: | Single Protein |
| Type: | anti-fibrotic |
| Molecular Function: | DNA-binding |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other transcription factor | Transcription activator |
Reference Record 1
| PubMed ID | 20625373 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | Targeting TGF-β signaling | ||
Reference Record 2
| PubMed ID | 16956920 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3
| PubMed ID | 12761254 | Compound ID | |
| CAS | Name | ||
| Model | rat | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||