Uniprot ID: | O00327 |
Secondary ID: | A2I2N6 |
Symbol: | ARNTL |
Other Name: | BHLHE5,Basic-helix-loop-helix-PAS protein MOP3,Brain and muscle ARNT-like 1,Class E basic helix-loop-helix protein 5,bHLHe5,Member of PAS protein 3,PAS domain-containing protein 3,bHLH-PAS protein JAP3 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Activator,DNA-binding |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other transcription factor | Transcription activator |
Reference Record 1
PubMed ID | 26753996 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | EMT,cells migration | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β |