Aryl hydrocarbon receptor nuclear translocator-like protein 1

Basic Information


Uniprot ID: O00327
Secondary ID: A2I2N6
Symbol: ARNTL
Other Name: BHLHE5,Basic-helix-loop-helix-PAS protein MOP3,Brain and muscle ARNT-like 1,Class E basic helix-loop-helix protein 5,bHLHe5,Member of PAS protein 3,PAS domain-containing protein 3,bHLH-PAS protein JAP3
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Transcription activator

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26753996 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II EMT,cells migration
Process III prevenet collagen deposition
Mechanism Targeting TGF-β