| Uniprot ID: | P41134 |
| Secondary ID: | A8K537 |
| Symbol: | ID1 |
| Other Name: | BHLHB24,Class B basic helix-loop-helix protein 24,bHLHb24,Inhibitor of DNA binding 1,Inhibitor of differentiation 1 |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Developmental protein,Repressor |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other transcription factor | Transcription repressor |
Reference Record 1
| PubMed ID | 19741012 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | myofibroblasts differentiation | ||
| Process III | |||
| Mechanism | |||
Reference Record 2
| PubMed ID | 18583319 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
| Process I | |||
| Process II | myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3
| PubMed ID | 16628634 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Fibrosis |
| Process I | |||
| Process II | HSCs activation | ||
| Process III | |||
| Mechanism | Targeting TGF-β or BMP-2 signaling | ||