Transcription factor HES-1

Basic Information


Uniprot ID: Q14469
Secondary ID: Q6FHB2
Symbol: HES1
Other Name: BHLHB39,Class B basic helix-loop-helix protein 39,bHLHb39,Hairy and enhancer of split 1,Hairy homolog,Hairy-like protein,hHL
Class: Single Protein
Type: pro-fibrotic
Molecular Function: DNA-binding,Repressor


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Transcription repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 25624721 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II myofibroblasts activation
Process III
Mechanism