Uniprot ID: | P46937 |
Secondary ID: | B4DTY1 |
Symbol: | YAP1 |
Other Name: | YAP65,Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Activator,Repressor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other transcription factor | Both activator and repressor |
Reference Record 1
PubMed ID | 26574480 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | cells proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 2
PubMed ID | 25908270 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation | ||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 3
PubMed ID | 25502501 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | fibroblasts activation,fibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism |