Interferon regulatory factor 1

Basic Information


Uniprot ID: P10914
Secondary ID: Q96GG7
Symbol: IRF1
Other Name:
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding,Repressor


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Both activator and repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 24732887 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting IRF1-iNOS axis