Interferon regulatory factor 3

Basic Information


Uniprot ID: Q14653
Secondary ID: A8K7L2
Symbol: IRF3
Other Name:
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Both activator and repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28192879 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Keloid
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1/Smad signaling pathway