Uniprot ID: | Q14653 |
Secondary ID: | A8K7L2 |
Symbol: | IRF3 |
Other Name: | |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Activator,DNA-binding |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other transcription factor | Both activator and repressor |
Reference Record 1
PubMed ID | 28192879 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Keloid |
Process I | |||
Process II | fibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β1/Smad signaling pathway |