| Uniprot ID: | P18847 |
| Secondary ID: | Q5VTZ2 |
| Symbol: | ATF3 |
| Other Name: | cAMP-dependent transcription factor ATF-3,Activating transcription factor 3 |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | DNA-binding,Repressor |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other transcription factor | Both activator and repressor |
Reference Record 1
| PubMed ID | 28249877 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Map2K3 and p38 MAPK signaling | ||
Reference Record 2
| PubMed ID | 25589515 | Compound ID | |
| CAS | Name | ||
| Model | human,mice | Fibrosis Disease | Systemic sclerosis |
| Process I | |||
| Process II | fibroblasts activation,myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Smad signaling | ||
Reference Record 3
| PubMed ID | 23874609 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||