Krueppel-like factor 4

Basic Information


Uniprot ID: O43474
Secondary ID: B2R8S4
Symbol: KLF4
Other Name: EZF,Epithelial zinc finger protein EZF,Gut-enriched krueppel-like factor
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Activator,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Both activator and repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26839446 Compound ID
CAS Name
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting PAI-1

Reference Record 2

PubMed ID 25892014 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II EMT
Process III
Mechanism

Reference Record 3

PubMed ID 29158503 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II EMT
Process III prevenet collagen deposition
Mechanism