Uniprot ID: | O43474 |
Secondary ID: | B2R8S4 |
Symbol: | KLF4 |
Other Name: | EZF,Epithelial zinc finger protein EZF,Gut-enriched krueppel-like factor |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Activator,DNA-binding |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other transcription factor | Both activator and repressor |
Reference Record 1
PubMed ID | 26839446 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | EMT | ||
Process III | |||
Mechanism | Targeting PAI-1 |
Reference Record 2
PubMed ID | 25892014 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | EMT | ||
Process III | |||
Mechanism |
Reference Record 3
PubMed ID | 29158503 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | EMT | ||
Process III | prevenet collagen deposition | ||
Mechanism |