Uniprot ID: | P54821 |
Secondary ID: | B5BUM7, O60807 |
Symbol: | PRRX1 |
Other Name: | PMX1,Homeobox protein PHOX1,Paired-related homeobox protein 1,PRX-1 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Developmental protein,DNA-binding |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other transcription factor | Both activator and repressor |
Reference Record 1
PubMed ID | 18296734 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation | ||
Process III | |||
Mechanism | Targeting collagen a 1(I) |