Paired mesoderm homeobox protein 1

Basic Information


Uniprot ID: P54821
Secondary ID: B5BUM7, O60807
Symbol: PRRX1
Other Name: PMX1,Homeobox protein PHOX1,Paired-related homeobox protein 1,PRX-1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Developmental protein,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Both activator and repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 18296734 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III
Mechanism Targeting collagen a 1(I)