Polypyrimidine tract-binding protein 1

Basic Information


Uniprot ID: P26599
Secondary ID: Q9BUQ0
Symbol: PTBP1
Other Name: PTB,PTB,57 kDa RNA-binding protein PPTB-1,Heterogeneous nuclear ribonucleoprotein I,hnRNP I
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,Repressor,RNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Both activator and repressor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27897224 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Keloid
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism