| Uniprot ID: | O43734 |
| Secondary ID: | B2RAY9 |
| Symbol: | TRAF3IP2 |
| Other Name: | C6orf2,Connection to IKK and SAPKJNK,Nuclear factor NF-kappa-B activator 1,ACT1,TRAF3-interacting protein 2 |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Adaptor protein |
Reference Record 1
| PubMed ID | 28053087 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 27040306 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3
| PubMed ID | 26148936 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation,fibroblasts migration | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting IKK, JNK, NF-κB/p65 and AP-1 | ||
Reference Record 4
| PubMed ID | 23872479 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | fibroblasts migration,fibroblasts differentiation | ||
| Process III | |||
| Mechanism | Targeting NF-κB and AP-1 | ||
Reference Record 5
| PubMed ID | 22575763 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||