Uniprot ID: | P46531 |
Secondary ID: | Q59ED8, Q5SXM3 |
Symbol: | NOTCH1 |
Other Name: | TAN1,Notch 1,hN1,Translocation-associated notch protein TAN-1,NEXT,NICD,Notch 1 extracellular truncation,Notch 1 intracellular domain,NEXT,NICD |
Class: | Single Protein |
Type: | pro/anti-fibrotic |
Molecular Function: | Activator,Developmental protein,Receptor |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other intracellular receptor |
Reference Record 1
PubMed ID | 23166366 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 2
PubMed ID | 19349363 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | myofibroblasts differentiation | ||
Process III | prevenet collagen deposition | ||
Mechanism |