Neurogenic locus notch homolog protein 1

Basic Information


Uniprot ID: P46531
Secondary ID: Q59ED8, Q5SXM3
Symbol: NOTCH1
Other Name: TAN1,Notch 1,hN1,Translocation-associated notch protein TAN-1,NEXT,NICD,Notch 1 extracellular truncation,Notch 1 intracellular domain,NEXT,NICD
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: Activator,Developmental protein,Receptor


Target Classification


Category I Category II Category III
Intracellular Other intracellular receptor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 23166366 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 19349363 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism