Sequestosome-1

Basic Information


Uniprot ID: Q13501
Secondary ID: A6NFN7
Symbol: SQSTM1
Other Name: ORCA,EBI3-associated protein of 60 kDa,EBIAP,p60,Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa,Ubiquitin-binding protein p62
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Apoptosis,Autophagy,Differentiation,Immunity


Target Classification


Category I Category II Category III
Intracellular Other intracellular receptor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27728806 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II HSC activation
Process III prevenet collagen deposition
Mechanism Targeting vitamin D receptor