Uniprot ID: | Q96AC1 |
Secondary ID: | B5TJY2, Q14840, Q86TY7 |
Symbol: | FERMT2 |
Other Name: | KIND2,Kindlin-2,Mitogen-inducible gene 2 protein,MIG-2,Pleckstrin homology domain-containing family C member 1,PH domain-containing family C member 1 |
Class: | Single Protein |
Type: | pro/anti-fibrotic |
Molecular Function: | Cell adhesion,Cell shape,Wnt signaling pathway |
Category I | Category II | Category III |
---|---|---|
Intracellular | Structural protein |
Reference Record 1
PubMed ID | 24226523 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | EMT | ||
Process III | |||
Mechanism | Targeting ERK1/2 and Akt |
Reference Record 2
PubMed ID | 23723426 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting TGF-β/Smad signaling |
Reference Record 3
PubMed ID | 28775002 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | cells apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism |