NAD-dependent protein deacetylase sirtuin-2

Basic Information


Uniprot ID: Q8IXJ6
Secondary ID: A8K3V1
Symbol: SIRT2
Other Name: SIR2L,Regulatory protein SIR2 homolog 2,SIR2-like protein 2
Class: Epigenetics
Type: anti-fibrotic
Molecular Function: Hydrolase


Target Classification


Category I Category II Category III
Intracellular Epigenetics Eraser

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28947430 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting AMPK