Uniprot ID: | |
Secondary ID: | |
Symbol: | miR-17 |
Other Name: | |
Class: | Epigenetics |
Type: | pro/anti-fibrotic |
Molecular Function: |
Category I | Category II | Category III |
---|---|---|
Intracellular | Epigenetics | microRNA |
Reference Record 1
PubMed ID | 27541364 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cystic fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 2
PubMed ID | 26637809 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation | ||
Process III | |||
Mechanism | Targeting Wnt/β-catenin pathway |
Reference Record 3
PubMed ID | 26160865 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cystic fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | |||
Mechanism | Targeting IL-18 |
Reference Record 4
PubMed ID | 25915722 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,HSCs proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism |