| Uniprot ID: | |
| Secondary ID: | |
| Symbol: | miR-29a |
| Other Name: | |
| Class: | Epigenetics |
| Type: | anti-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Epigenetics | microRNA |
Reference Record 1
| PubMed ID | 28577867 | Compound ID | |
| CAS | Name | ||
| Model | rat | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β1 signaling and Smad2/3 | ||
Reference Record 2
| PubMed ID | 27480597 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSC activation,cells proliferation,cells migration | ||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 27328306 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Dermal fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting COL7A1 | ||
Reference Record 4
| PubMed ID | 25923107 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 5
| PubMed ID | 27060017 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | |||
| Mechanism | Targeting VEGF-A/MAPK signal pathway | ||
Reference Record 6
| PubMed ID | 26700017 | Compound ID | |
| CAS | Name | ||
| Model | rat | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 7
| PubMed ID | 26095125 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Pancreatic fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 8
| PubMed ID | 25892183 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Muscle fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting PTEN and SPRY-1 | ||
Reference Record 9
| PubMed ID | 25549087 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Systemic sclerosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | Targeting TAB1 | ||
Reference Record 10
| PubMed ID | 23459615 | Compound ID | |
| CAS | Name | ||
| Model | human,mice,canine | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 11
| PubMed ID | 22565577 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Liver fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 12
| PubMed ID | 22434133 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Muscle fibrosis |
| Process I | |||
| Process II | myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting MFAP and YY1 | ||
Reference Record 13
| PubMed ID | 22395530 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β/Smad3 signaling | ||
Reference Record 14
| PubMed ID | 21511916 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting microRNA-29a | ||
Reference Record 15
| PubMed ID | 20201077 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Systemic sclerosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting COL3A1 | ||