Uniprot ID: | |
Secondary ID: | |
Symbol: | miR-29a |
Other Name: | |
Class: | Epigenetics |
Type: | anti-fibrotic |
Molecular Function: |
Category I | Category II | Category III |
---|---|---|
Intracellular | Epigenetics | microRNA |
Reference Record 1
PubMed ID | 28577867 | Compound ID | |
CAS | Name | ||
Model | rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β1 signaling and Smad2/3 |
Reference Record 2
PubMed ID | 27480597 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSC activation,cells proliferation,cells migration | ||
Process III | |||
Mechanism |
Reference Record 3
PubMed ID | 27328306 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Dermal fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting COL7A1 |
Reference Record 4
PubMed ID | 25923107 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 5
PubMed ID | 27060017 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts proliferation | ||
Process III | |||
Mechanism | Targeting VEGF-A/MAPK signal pathway |
Reference Record 6
PubMed ID | 26700017 | Compound ID | |
CAS | Name | ||
Model | rat | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 7
PubMed ID | 26095125 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Pancreatic fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 8
PubMed ID | 25892183 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Muscle fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting PTEN and SPRY-1 |
Reference Record 9
PubMed ID | 25549087 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting TAB1 |
Reference Record 10
PubMed ID | 23459615 | Compound ID | |
CAS | Name | ||
Model | human,mice,canine | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 11
PubMed ID | 22565577 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Liver fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 12
PubMed ID | 22434133 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Muscle fibrosis |
Process I | |||
Process II | myofibroblasts differentiation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting MFAP and YY1 |
Reference Record 13
PubMed ID | 22395530 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β/Smad3 signaling |
Reference Record 14
PubMed ID | 21511916 | Compound ID | |
CAS | Name | ||
Model | vitro,mice,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting microRNA-29a |
Reference Record 15
PubMed ID | 20201077 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting COL3A1 |