microRNA-34a

Basic Information

Uniprot ID:
Secondary ID:
Symbol: miR-34
Other Name:
Class: Epigenetics
Type: pro/anti-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Intracellular Epigenetics microRNA

Related Compound

Fibrosis Related Property

Reference Record 1

PubMed ID 28796252 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Airway fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting Nur77-mediated autophagy

Reference Record 2

PubMed ID 28273432 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting p53-miR-34a

Reference Record 3

PubMed ID 27979858 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism Targeting Sirt1,E2F3 and cyclin E2

Reference Record 4

PubMed ID 27977785 Compound ID
CAS Name
Model vitro Fibrosis Disease Retinal fibrosis
Process I
Process II cells proliferation
Process III
Mechanism Targeting LGR4

Reference Record 5

PubMed ID 26437572 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III
Mechanism Targeting ACSL1

Reference Record 6

PubMed ID 25370690 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III
Mechanism Targeting PPARγ

Reference Record 7

PubMed ID 24986745 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 8

PubMed ID 22363487 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Renal fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting the Notch signaling pathway