Uniprot ID: | |
Secondary ID: | |
Symbol: | miR-101 |
Other Name: | |
Class: | Epigenetics |
Type: | anti-fibrotic |
Molecular Function: |
Category I | Category II | Category III |
---|---|---|
Intracellular | Epigenetics | microRNA |
Reference Record 1
PubMed ID | 28726637 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | fibroblasts activation,fibroblasts proliferation,myofibroblasts differentiation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting NFATc2 and SMAD2/3 signaling |
Reference Record 2
PubMed ID | 28577867 | Compound ID | |
CAS | Name | ||
Model | rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β1 signaling and Smad2/3 |
Reference Record 3
PubMed ID | 26628091 | Compound ID | |
CAS | Name | ||
Model | zebrafish | Fibrosis Disease | Scar |
Process I | |||
Process II | cells proliferation | ||
Process III | |||
Mechanism |
Reference Record 4
PubMed ID | 25808945 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | EMT,cells proliferation,cells migrations | ||
Process III | |||
Mechanism |
Reference Record 5
PubMed ID | 25591764 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts proliferation,fibroblasts migration | ||
Process III | |||
Mechanism | Targeting TGFβRI |
Reference Record 6
PubMed ID | 24817606 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,HSCs proliferation,HSCs migration,cells apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGFβ signaling |
Reference Record 7
PubMed ID | 22811578 | Compound ID | |
CAS | Name | ||
Model | vitro,mice,rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting c-Fos/TGFβ1 pathway |